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Nanoscale hydroxyapatite/chitosan polymer coatings: Synthesis and characterization

The effect of pulsed electrodeposition method parameters on optimum coating of nanohydroxyapatite/chitosan composite.The present work involves the coating synthesis of nano?hydroxyapatite/chitosan (nHA/CS) on a Mg?2?wt% Zn scaffold with the pulse electrodeposition (PED) technique. In practice, to render coatings more corrosion?resistant and biocompatibility in simulated body fluids, the impact of PED factors, such as mean current density (j), a duty cycle, and coating duration (t), was investigated. Further, Fourier transform infrared spectroscopy, scanning electron microscope, x?ray diffraction, energy?dispersion spectrometer, and water contact angle (WCA) were studied to characterize coatings. The corrosion resistance of coatings was investigated by impedance evaluations and potentiodynamic polarization. The results obtained from analyses revealed that the optimum conditions for synthesizing the nHA/CS coating were achieved when applying j?=?20?mA/cm2, a duty cycle?=?0.4, and a duration of 60?minutes. The coatings' microstructure and Ca/P ratio were influenced by PED factors, which included nano spherical?shaped and 1.65. Furthermore, the corrosion rate was decreased from 19.603 to 1.492?mm?yr?1 after being modified by optimum coating. Moreover, the high hydrophilic properties are assigned to this coating with a WCA of 29.9 compared to other coatings and the Mg scaffold. The biological properties of the optimum coating were assessed through in?vitro experiments involving MG63 cells, which included the evaluations of cell adhesion and cytotoxicity. The results obtained from the corrosion and in?vitro experiments indicate that the nanocomposite coating, upon optimization, holds potential as a scaffold for bone tissue engineering.HighlightsUsing Mg?2?wt% Zn scaffold as a substrate for nanocomposite coatings.Pulse electrodeposition method for the synthesis of nano?hydroxyapatite/chitosan (nHA/CS) coatings.Pulse electrodeposition (PED) method to modify morphology, corrosion resistance, and biocompatibility.Optimum PED parameters: j?=?20?mA/cm2, duty cycle?=?0.4, and t?=?60?min.

Publication date: 21/09/2023

Polymer Composites


This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 870292.