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Poly(2-oxazoline)s: synthesis and biomedical applications

With the advancement of medical technology, the previous biomedical material platforms have been unable to meet the increasingly diverse application requirements, and the emergence of poly(2-oxazoline)s provides an opportunity to develop the next generation of biomedical materials. The highly tunable structure and function of poly(2-oxazoline)s, with excellent physical and biological properties, have shown great potential for application in the initial exploratory work. Currently, there are a lot of applied studies related to the water solubility, invisibility, and thermoresponsive of poly(2-oxazoline)s, mainly focused on drug delivery, protein modification, gene carriers, anti-fouling interface, cell sheet engineering, and hydrogel. This paper describes the preparation and physicochemical properties of poly(2-oxazoline)s and reviews the recent applications of poly(2-oxazoline)s in the biomedical field.

Graphical abstract

Publication date: 06/02/2023

Reference: 10.1007/s13233-023-00116-x

Macromolecular Research


This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 870292.