Deep Learning as a Compass for Industrial Biocatalysis: The Grase Framework Rewrites the Rules for Polyurethane Recycling
Graphical Abstract and Lay SummaryThe GRASE deep?learning framework overcomes the enzyme activity–stability trade?off to discover AbPURase, a robust biocatalyst that efficiently depolymerizes polyurethane waste in harsh industrial conditions, enabling scalable, closed?loop chemical recycling.